（商品説明）

*画像の写真は5mlの商品ですが、お送りする商品は6ml容量の商品です。

有効成分プロゲステロンが 排卵と発情症状を予防するステロイド薬。

＜適応症＞

犬：発情の予防、偽妊娠の予防、月経過多。

猫：発情予防、月経過多、リンパ腫の予防。

在庫保有不可能商品ですので、御注文後、所定の手続きを経て後、取り寄せ発送となります。

注文確定後お手元に届くまでおおよそ１４日～２０日ほどかかります。

（使用法）

犬：1 ml（50 mg）を無病期間中に皮下注射し、3〜4か月ごとに繰り返します。

大型犬（> 45kg）の場合は1.5  -  2ml（75  -  100mg）がおおよその目安。

猫：1週間に1ml（50 mg）皮下脂肪のない期間、3  -  4ヶ月ごとに繰り返す

 月経過多およびリンパ腫：1ml（50mg）を目安に皮下注射。

 ＊猫は、発情停止中、または子猫が母猫から連れ出されたときにいつでも治療することができます。

生体個体差、症状により投与量、投与回数は異なる場合がありますので、必ず獣医師の指導監督のもと、その指示に従いご使用下さい。

＜有害反応＞

デポプロモンを投与した後、注射部位でコートの軽い変色、またはわずかな脱毛が起こり得る。少ないで管理する

＜注意事項＞

生殖年齢の女性は、製品を取り扱う際に製品との接触を避けるか、プラスチック製の手袋を着用する必要があります。製品が肌に触れた場合は、水と石鹸で洗ってください。製品が目に入ったときは、洗い流してください。

水。誤って自己注射した場合は、医師に相談して下さい。

＜使用上の注意＞

次のような場合は投与しないでください。

・発情前期、発情期および発情期。性器の感染、乳房の腫瘍、性的に成熟していない動物、繁殖用の家畜、妊娠中の動物、糖尿病のある動物、Depo Promoneに過敏な動物、そして乳首の腫れに苦しむ人や授乳中の人間。

・25℃以下で保存してください。開けられたびんの貯蔵寿命12週です。子供の手の届かないところや目に入らないようにしてください。

（使用期限）

ご注文日より１年以上有効のもの

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DEPOGESTON 6ml vial for Dogs and Cats

*The images is the product contained 5ml, but we send you it contained 6ml.

DESCRIPTION

50 mg/ml, contraceptive suspension for injection for dogs and cats

Active substance and excipient content

Active substance:

Medroxyprogesterone acetate   –   50 mg/ml

Excipients:

Methyl parahydroxybenzoate  – 1.2 mg/ml

Propyl parahydroxybenzoate – 0.2 mg/ml

Therapeutic indications

Preventing heat in bitches and queens.

Treating hypersexuality in queens, not associated with polycystic ovaries.

Contraindications

Do not use:

–    in proestrus, oestrus, metoestrus phases,

–    in pregnant and lactating animals,

–    in case of diagnosed mammary gland tumours,

–    in immature and growing animals,

–    before occurrence of the first heat cycle,

–    in diabetic animals,

–    in reproductive tract inflammations,

–    in English Whippet bitches,

–    in cases of hypersensitivity to the active substance or any of the excipients.

Adverse reactions

Administration of medroxyprogesterone for more than 2 years is conducive to uterus and mammary gland disorders. It may cause endometritis pyometra complex in bitches, growth of endometrial tissue, cystic endometrial hyperplasia, polycystic ovaries, acromegaly and mammary gland tumours. Administration of MPA may cause adrenal suppression and diabetes.

Transitory changes in animal temperament and increased appetite may occur during treatment.

In rare cases, skin and fur discolouration or hyperpigmentation may occur at the injection site. Any adverse reactions emerged after administration of the product or any observed symptoms not listed in the leaflet (including symptoms reported in humans following exposure to the product) should be reported to the competent veterinarian, Marketing Authorization Holder or the Office for Registration of Medicinal Products, Medical Devices and Biocidal Products. The report form should be downloaded from https://www.urpl.gov.pl (Department of Veterinary Medicinal Products).

Amount to be administered per species, method and route of administration

Depogeston should be administered subcutaneously or intramuscularly in the following doses:

bitches: 50 – 100 mg of medroxyprogesterone acetate per animal, subcutaneously or intramuscularly, i.e.

– small animals (up to 10 kg of b.w.) – 1.0 ml of the product per animal;

– medium (10-25 kg of b.w.) – 1.5 ml of the product per animal;

– large (25-45 kg of b.w.) – 2.0 ml of the product per animal;

queens: 50 mg of medroxyprogesterone acetate per animal, subcutaneously, i.e. 1.0 ml of the product per animal.

First administration of the product should occur not earlier than after 2 months after parturition and not later than 1 month before expected heat.

In order to permanently block the heat cycle, apply this product regularly every 5 months in bitches and every 3-4 months in queens, however not longer than for the period of 2 years. Inform the animal owner that occurrence of the first heat is animal-specific and it usually occurs after about 5-6 months in bitches and 3-4 months in queens, although in some cases this period may be considerably extended.

Instructions for use

Shake the product before use to obtain homogeneous suspension.

Withdrawal period

Not applicable

Special precautions for storage

Keep out of the sight and reach of children.

Store below 25°C. Do not freeze.

Do not use this product after the use-by date given on the label.

Shelf life after first opening the immediate packaging: 14 days

Special warnings

Special warnings per target species:

Relevant laboratory tests to determine the phase of the cycle should be run before use.

Special precautions for use in animals:

First administration of the product should occur not earlier than after 2 months after parturition and not later than 1 month before expected heat. 

Special precautions to be taken by the person administering the veterinary medicinal product to animals:

Pregnant women and women of childbearing potential should avoid exposure to the product. In case of accidental spilling on skin or contact with eyes, rinse the affected site with water. In case of accidental self-injection, immediately seek doctor’s assistance and present the doctor with the information leaflet or package.

Pregnancy:

Do not use during pregnancy.

Lactation:

Do not use while breastfeeding. If administered during breastfeeding, the product suppresses milk secretion by inhibiting secretion of pituitary gonadotropins.

Interaction with other medicinal products and other forms of interaction:

Administration of gonadotropins (LH, FSH) and estrogens for purposes of recovering the heat cycle after product use may increase the risk of pathological lesions of the endometrium.

Overdose (symptoms, emergency procedures, antidotes):

Overdose may cause transitory changes in animal temperament, increased appetite, lactation.

Pharmaceutical incompatibilities:

In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.

Special precautions for the disposal of unused veterinar