（商品説明）

イギリス製のハイグレード品

人間用医薬品ですが、犬や猫の動物にも使用可能です。

有効成分スピロノラクトンが犬や猫の心疾患、肝疾患などで起こる体液の蓄積や浮腫を軽減、抑制する等、特定の作用を有する利尿剤です。

また心臓に有害な作用を及ぼすアルドステロンの活性も阻害し尿に増加したナトリウム排出を引き起こし、体内カリウムは保持したまま、余分な水分を尿として生産、排出させる利尿作用があります。

心疾患で起こる液体の蓄積を減らすとともに肝疾患に関連する液体膨張（腹水）の処置にも使用、高血圧を抑える働きもあります。

（使用法）

猫や犬に対し、症状や生体差に応じて0.5～4mg/kgを目安に毎日１～２回投与。

<使用上の注意>

・かかりつけの獣医師の指示に応じて使用されることをお薦め致します。

・使用量や試用期間は症状、薬への反応、副作用の出方などによって異なります。

・スピロノラクトンに過敏反応を示したり、アレルギー反応を示す場合は直ちに使用を中止して下さい。

・腎臓の損傷や肝疾患、アジソン病、血中カリウム濃度が強過ぎる場合は使用をお控え下さい。

（使用期限）

ご注文より１年以上有効のもの

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Spironolactone25mg28tabs by actavis

What is Spironolactone?

Spironolactone is in the family of medications known as diuretics (water pill). It blocks the effects of the hormone aldosterone, resulting in water loss by the kidneys, and may decrease scarring/ fibrosis within the heart muscle. It is classified as a potassium sparing diuretic, as it also increases the amount of potassium retained by the kidneys.

Uses/Indications

Used to delay onset of congestive heart failure in cases of degenerative valve disease and dilated cardiomyopathy

Often used along with lasix in the treatment of congestive heart failure in both dogs and cats, especially in patients with low potassium levels

Also used in certain adrenal gland diseases (hyperaldosteronism) and in some cases of abdominal fluid secondary to low blood protein levels

Adverse Effects

[please contact CVCA should any of these symptoms be noted]

Loss of appetite, vomiting or diarrhea are the most common side effects

Minty taste can cause drooling in cats

Can result in high potassium levels, especially when used with an ACEi (enalapril/benazepril)

Dehydration and increases in kidney values infrequently noted

Facial itching as an uncommon side effect in cats

Client Information

Recommended to be given with food due to its bitter taste, especially in cats

Comes in a tablet form, but can be reformulated into chewables or flavored liquid

Please contact CVCA should your pet require anesthesia, as dose adjustments may be necessary

Close monitoring of blood chemistry profiles are indicated to monitor kidney function and potassium levels

Contraindicated in patients with Addison’s disease or elevated potassium levels

Interactions with Other Drugs

Potential for high potassium levels when used with an ACEi (enalapril, benazepril)

Can increase digoxin levels

Concurrent use of a nonsteroidal antinflammatories (Rimadyl, Deramaxx, Metacam) may decrease the effectiveness

The doctors at CVCA have taken this into account, however, please feel free to contact CVCA regarding any concurrent medications your pet may be prescribed

Standard Dosage Forms

Spironolactone Tablets – 100mg

Synonyms

(Spironolactone, Aldactone)